BEpro (formerly known as PEPITO) is a predictor of discontinuous B-cell epitopes. All that is required is the tertiary structure of the antigen, in the PDB format.
Users can request either a text file with a simplified PDB containing the predicted epitope score in the temperature field (i.e., the last column) or a visualization of the protein using Jmol colored by the epitope score.
Higher scores correspond to a higher likelihood that the residue is in an epitope.
Details on the performance of BEpro on the Discotope Dataset can be found here.
Details on the performance of BEpro on the Epitome Dataset can be found here.
If you use BEpro, please cite:
M. Sweredoski, P. Baldi, "PEPITO: Improved Discontinuous B-cell Prediction Using Multiple Distance Thresholds and Half Sphere Exposure".
BEpro uses Jmol to visualize the epitope predictions. For more information on Jmol, visit http://www.jmol.org
If you have addtional questions about BEpro, please contact email@example.com
M. J. Sweredoski and P. Baldi. PEPITO: Improved Discontinuous B-Cell Epitope Prediction Using Multiple Distance Thresholds and Half-Sphere Exposure. Bioinformatics, 24, 12, 1459-1460, (2008).
For commercial license, please contact: igb-license [at] ics [.] uci [.] eduReturn to the submission page